Increased contact transmission of contemporary Human H5N1 compared to Bovine and Mountain Lion H5N1 in a hamster model
These findings demonstrate that the Syrian hamster model complements existing animal models for influenza A virus research and expands the resources available for investigating the pathogenicity, transmissibility, and efficacy of countermeasures.
Polymerase trapping as the mechanism of H5 highly pathogenic avian influenza virus genesis
High-pathogenicity influenza viruses have not only been devastating the planet’s wild and domestic bird populations, but they also represent a persistent threat of initiating a fatal human influenza pandemic.
Avian influenza: detections in birds decline across the EU
According to the latest quarterly monitoring report from EFSA, ECDC and the EURL, the number of recorded outbreaks is higher overall than recent years for the same period. The risk for the general public remains low.
Stabilization of the H5 clade 2.3.4.4b hemagglutinin improves vaccine-elicited neutralizing antibody responses in mice
These findings highlight that H5 HA–stabilizing mutations enhance the quality of antibody responses across different vaccine formats, underscoring their potential to improve pandemic preparedness vaccines.
